Advances in Screening and Prevention in Reproductive Cancers (ASPIRE)
Self-collection based cervical cancer screening in an urban centre of Uganda
Cervical cancer is the second most common cancer in women living in low and middle income countries, where around 85% of cases occur globally. Uganda has one of the highest cervical cancer rates in the world.
ASPIRE is a women’s health initiative that uses innovative models and technologies to improve access to reproductive health in low income settings. Since 2007, ASPIRE has conducted various community-based cervical cancer screening initiatives in Kisenyi, Uganda using self-collection based HPV testing. The project takes an integrated health services approach to address cervical cancer and other reproductive health issues including sexually transmitted infections and HIV.
Mitchell SM, Pedersen HN, Eng Stime E, Sekikubo M, Moses E, Mwesigwa D, Biryabarema C, Christilaw J, Byamugisha JK, Money DM, Ogilvie GS. Self-collection based HPV testing for cervical cancer screening among women living with HIV in Uganda: a descriptive analysis of knowledge, intentions to screen and factors associated with HPV positivity. BMC Womens Health. 2017 Jan 13;17(1):4.
Mitchell SM, Pedersen HN, Sekikubo M, Biryabarema C, Byamugisha JJ, Mwesigwa D, Steinberg M, Money DM, Ogilvie GS: Strategies for community education prior to clinical trial recruitment for a cervical cancer screening intervention in Uganda. Frontiers in Oncology. 2016; 6.
Moses E, Pedersen HN, Mitchell SM, Sekikubo M, Mwesigwa D, Singer J, Biryabarema C, Byamugisha JK, Money DM, Ogilvie GS. Uptake of community-based, self-collected HPV testing vs. visual inspection with acetic acid for cervical cancer screening in Kampala, Uganda: Preliminary results of a randomized controlled trial. Trop Med Int Health. 2015; 20(10):1355-67.
Teng FF, Mitchell SM, Sekikubo M, Biryabarema C, Byamugisha JK, Steinberg M, Money DM, Ogilvie GS. Understanding the role of embarrassment in gynaecological screening: a qualitative study from the ASPIRE cervical cancer screening project in Uganda. BMJ Open 2014;4:4 e004783.
Mitchell SM, Sekikubo M, Biryabarema C, Byamugisha JJ, Steinberg M, Jeronimo J, Money DM, Christilaw J, Ogilvie GS. Factors associated with high-risk HPV positivity in a low-resource setting in sub-Saharan Africa. Am J Obstet Gynecol 2014 Jan;210(1):81.e1-7.
Ogilvie G S, Mitchell S, Sekikubo M, Biryabarema C, Byamugisha J, Jeronimo J, Miller D, Steinberg M, Money D M. Results of a community-based cervical cancer screening pilot project using human papillomavirus self-sampling in Kampala, Uganda. Int J Gynaecol Obstet 2013; 122 (2): 118–123.
Mitchell S, Ogilvie G, Steinberg M, Sekikubo M, Biryabarema C, Money D. Assessing women’s willingness to collect their own cervical samples for HPV testing as part of the ASPIRE cervical cancer screening project in Uganda. Int J Gynaecol Obstet 2011;114(2):111-115.
Ogilvie G, Krajden M, Maginley J, Isaac-Renton J, Hislop G, Elwood-Martin R et al. Feasibility of self-collection of specimens for human papillomavirus testing in hard-to reach women. CMAJ 2007;177(5):480-483.