Self-Collection in Guatemala
Self-Collection Based Screening in Guatemala
The aim of the HPV MES (multi-ethnic study) is to assess the acceptability, feasibility, and value of HPV self-collection program implementation in rural communities in Guatemala. The 2015 pilot study found very high rates of self-collection acceptability among 202 women residing in a Mayan community on Lake Atitlan with over 90% wanting to self-collect. This study was replicated in 2016, expanding to a multi-ethnic community on the Caribbean coast, as well as in the original study site. This study found different rates of willingness to test between the two communities (over 90% in Santiago, but only 53% in Livingston choosing to self-collect), but among women who chose to self-collect acceptability rates were comparable. Furthermore, in this expansion study, more affordable HPV testing options were used, demonstrating the feasibility of implementation of HPV self-collection programs in this setting.
The study team continued data collection in 2017 by re-contacting women from the expansion study to assess whether HPV testing increased rates of recommended follow-up screening (with either a Pap or VIA) in the year post-participation in the study.
Preliminary analyses suggest that women were more likely to receive a Pap or VIA in the year post-participation in the study, particularly if they received a positive HPV result, than in the year prior to participation. The data collected from the HPV MES study thus far suggests that HPV self-collection programs in rural areas in Guatemala would likely be acceptable to women, feasible to implement, and a valuable measure in reducing cervical cancer rates in the area.
Gottschlich A, Rivera-Andrade A, Grajeda E, Alvarez C, Montano CM, Meza R. Acceptability of human papillomavirus self-sampling for cervical cancer screening in an indigenous community in Guatemala. JGO. 2017 Oct; 5:444-454.